Skills are the modifiers for a Characters interactions with Props, Weapons, and Items. Each of these has a corresponding Skill that will affect their effectiveness.
For most Prop and Item interactions, there is a base chance of Success/Failure upon use. A higher level of the appropriate Skill will increase the chances of Success.
Each Attribute governs a different set of Skills, listed directly underneath that Attribute in the Character Screen (accessed by pressing the ‘C’ key).